Journal: Pulse
Submission Deadline: September 30, 2026
Arterial stiffness and central hemodynamics are pivotal determinants of cardiovascular risk, mediating myocardial load, coronary perfusion, cerebrovascular events, kidney dysfunction, and frailty. Over the past decades, methodological advances - from pulse wave analysis to imaging and tonometry - have matured our measurement standards and mechanistic insight. Today, AI/ML, big‑data pipelines, wearables, and digitally enabled care pathways are opening a new era of continuous, personalized hemodynamic assessment with the potential to transform hypertension diagnostics, therapy titration, and outcome prediction.
This article collection in Pulse aims to gather contributions that synthesize past lessons, present state‑of‑the‑art evidence, and chart future directions for research and clinical implementation.
Topics of interest include, but are not limited to:
- Measurement, Phenotyping, and Mechanisms: pulse wave velocity (carotid–femoral and regional), augmentation index, central systolic/diastolic pressures, reservoir‑excess pressure analysis; vascular aging trajectories; micro/macrovascular coupling; links to heart failure, CKD, stroke, cognitive decline.
- AI, Big Data, and Modeling: machine learning for risk stratification, TRIPOD‑AI/PROBAST‑AI‑aligned prognostic models; digital twins and physics‑informed ML for arterial tree modeling; multimodal fusion (hemodynamics + imaging + omics); generalization, calibration, and shift robustness.
- Wearables and Remote Monitoring: cuffless BP and surrogate hemodynamic indices; passive sensing; device validation frameworks; longitudinal adherence and clinical utility in routine care and population health.
- Trials and Implementation: adaptive and pragmatic trials of hemodynamic‑guided hypertension management; integration into EHRs/clinical decision support; implementation science; health equity and bias mitigation in AI‑enabled pathways.
- Therapeutic Strategies: pharmacologic and device‑based interventions guided by central hemodynamics; exercise and lifestyle programs targeting vascular stiffness; responder phenotypes and precision treatment.
Please select the option “Call for Papers: Arterial Stiffness and Hemodynamics - Past Lessons, Present Evidence, Future Directions” when submitting your manuscript and mention this Call for Papers in your cover letter.
Article publication is subject to rigorous peer review in line with the journal's editorial policies. Please refer to our author guidelines for further details about the publication conditions.
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