Journal: Cerebrovascular Diseases 

Submission Deadline: November 30, 2024

We are increasingly aware that frailty is associated with stroke risk and factors propagating this influence in the frail include:

  • Increased number and severity of stroke risk factors
  • Increased stroke complications and poorer stroke recovery
  • Increased severity of stroke
  • Decreased response to treatment

However, limited data exist on the above in certain stroke sub-types and we remain unclear as to how best to assess frailty in stroke, incorporate assessments into treatment decisions and understand some of the pathophysiological processes involved with transition from pre-stroke frailty to post-stroke frailty.

To date, the frailty in stroke literature has been dispersed across ageing, gerontology and cerebrovascular journals – this special issue offers a unique opportunity to homogenise the science and expertise to encourage engagement from cross-specialty collaborations to advance this field.

We welcome original research articles, brief reports, protocols, review articles, and letters presenting a perspective to advance the understanding of the role of frailty in stroke. Topics of interest are, but not strictly limited to, the following:

  • Frailty and stroke outcome, particularly in stroke sub-types including intracerebral haemorrhage, cerebral venous sinus thrombosis and subarachnoid haemorrhage.
  • Factors influencing propagation of frailty and stroke risk.
  • Pre-frailty and frailty trajectories for stroke survivors.
  • Reperfusion therapies and frailty as a modifier in stroke care.
  • Broader frailty considerations including cognitive, psychological and biological associations and mechanisms.


Please select the option “Call for Papers: Frailty in Stroke” when submitting your manuscript and mention this Call for Papers in your cover letter.

Cerebrovascular Diseases supports Open Access publications. Corresponding authors can publish Open Access articles at no or reduced cost if they are associated with or employed by one of these universities/institutions.

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