Journal: Oncology Research and Treatment 

Extended Submission Deadline: July 31, 2024

In the dynamic field of oncology, the influence of sex and gender remains a critical yet underexplored dimension. Historically, medical research has often overlooked these factors, leading to a one-size-fits-all approach in cancer treatment and care. However, recent advancements underscore the importance of understanding how both biological sex and sociocultural gender roles significantly influence cancer epidemiology, treatment efficacy, and patient outcomes.

Biological sex plays an undeniable role in oncology. Men and women exhibit different genetic, hormonal, and immunological profiles, which can lead to variations in e.g., cancer susceptibility and progression, pharmacodynamics and pharmacokinetics.

Gender – the roles, behaviors, and expectations society ascribes to men and women – also significantly impacts cancer care. Gender influences factors such as health-seeking behavior, access to healthcare, and adherence to treatment. For example, men are generally less likely to seek medical help or participate in preventive health screenings, potentially leading to later-stage diagnoses and poorer prognoses. Women might face gender-based disparities in the recognition and treatment of their symptoms. The importance of investigating the impact of sex and gender in oncology is twofold:

Firstly, it enables the development of more effective, personalized treatment strategies. Recognizing sex-based biological differences can guide the selection of therapeutic agents and dosing regimens, potentially improving treatment efficacy and reducing adverse effects. Secondly, understanding gender-related aspects can enhance patient care and support. Tailoring psychosocial interventions to address gender-specific needs and challenges can significantly improve patient well-being and treatment compliance.

To fully harness these benefits, a concerted effort is needed in oncological research and practice. This includes conducting sex-disaggregated research, developing gender-sensitive treatment protocols, and implementing policies that address gender disparities in healthcare access and quality. The investigation of sex and gender in oncology is not a mere academic pursuit; it is a necessity for advancing cancer care. By embracing these complexities, the medical community can move towards more personalized, effective, and equitable cancer treatment and support for all patients.

We are calling for contributions to an article collection dedicated to emerging insights on clinical and research questions that address the critical impact of sex and gender in cancer diagnosis and treatment. We will consider original research articles, brief reports, and review articles.

The accepted papers will be published in an article collection in Oncology Research and Treatment entitled “Beyond Biology: The Crucial Role of Sex and Gender in Oncology”.

Please select the option “Call for Papers: Beyond Biology: The Crucial Role of Sex and Gender in Oncology” when submitting your manuscript and mention this Call for Papers in your cover letter.

Oncology Research and Treatment supports Open Access publications. Corresponding authors can publish Open Access articles at no or reduced cost if they are associated with or employed by one of these universities/institutions.

Check out the Author Guidelines.